LING01 Gene Analysis in Parkinson's Disease Phenotypes
Identifieur interne : 001880 ( Main/Exploration ); précédent : 001879; suivant : 001881LING01 Gene Analysis in Parkinson's Disease Phenotypes
Auteurs : Oswaldo Lorenzo-Betancor [Espagne] ; Lluís Samaranch [Espagne] ; Elena Garcia-Martin [Espagne] ; Sebastian Cervantes [Espagne] ; Jose A. G. Agundez [Espagne] ; Félix J. Jimenez-Jimenez [Espagne] ; Hortensia Alonso-Navarro [Espagne] ; Antonio Luengo [Espagne] ; Francisco Coria [Espagne] ; Elena Lorenzo [Espagne] ; Jaione Irigoyen [Espagne] ; Pau Pastor [Espagne]Source :
- Movement disorders [ 0885-3185 ] ; 2011.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: Parkinson's disease (PD) and essential tremor (ET) may share some etiopathogenic factors. A genome-wide association study has shown that LINGO1 gene variants are associated with increased risk of ET. We hypothesized that LINGO1 variants could increase susceptibility to PD. Methods: A large series of PD subjects and healthy controls were genotyped for rs9652490 and rs11856808 LINGO1 single nucleotide polymorphisms (SNPs). Results: We found an increased frequency of the rs11856808T/T genotype in PD compared with controls (odds ratio = 1.46; corrected P value = 0.02). A recessive genetic model was the best fit for rs11856808 influence on PD (recessive gene action test: corrected P value = 0.01). Stratification analysis showed that rs11856808T/T genotype frequency was higher in the tremor-dominant PD and the classical PD (C-PD) subgroups (recessive gene action test for the C-PD subgroup: corrected P value = 0.004). Discussion: Our results indicate that LINGO1 variants could increase risk of PD, specifically those presenting the non-rigid-akinetic phenotypes, which suggests that LINGO1 may have a role in the etiology of tremor in PD at least in the Spanish population.
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G." last="Agundez">Jose A. G. Agundez</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>RIRMF/RETICS, Redes Temáticas de Investigación Cooperativa en Salud, Instituto de Salud Carlos III</s1><s3>ESP</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>RIRMF/RETICS, Redes Temáticas de Investigación Cooperativa en Salud, Instituto de Salud Carlos III</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Pharmacology, Medical School, University of Extremadura, Badajoz</s1><s3>ESP</s3><sZ>5 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Department of Pharmacology, Medical School, University of Extremadura, Badajoz</wicri:noRegion></affiliation></author><author><name sortKey="Jimenez Jimenez, Felix J" sort="Jimenez Jimenez, Felix J" uniqKey="Jimenez Jimenez F" first="Félix J." last="Jimenez-Jimenez">Félix J. Jimenez-Jimenez</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Department of Medicine-Neurology, Hospital Principe de Asturias, Universidad de Alcalá</s1><s2>Madrid</s2><s3>ESP</s3><sZ>6 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Neurology, Hospital del Sureste, Arganda del Rey</s1><s2>Madrid</s2><s3>ESP</s3><sZ>6 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Alonso Navarro, Hortensia" sort="Alonso Navarro, Hortensia" uniqKey="Alonso Navarro H" first="Hortensia" last="Alonso-Navarro">Hortensia Alonso-Navarro</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Neurology, Hospital La Mancha-Centro de Alcázar de San Juan</s1><s2>Ciudad Real</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Ciudad Real</wicri:noRegion></affiliation></author><author><name sortKey="Luengo, Antonio" sort="Luengo, Antonio" uniqKey="Luengo A" first="Antonio" last="Luengo">Antonio Luengo</name><affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Service of Neurology, Hospital Universitario La Princesa</s1><s2>Madrid</s2><s3>ESP</s3><sZ>8 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Coria, Francisco" sort="Coria, Francisco" uniqKey="Coria F" first="Francisco" last="Coria">Francisco Coria</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Clinic for Nervous System Disorders and Service of Neurology, Hospital Universitario Son Dureta</s1><s2>Palma de Mallorca</s2><s3>ESP</s3><sZ>9 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Palma de Mallorca</wicri:noRegion></affiliation></author><author><name sortKey="Lorenzo, Elena" sort="Lorenzo, Elena" uniqKey="Lorenzo E" first="Elena" last="Lorenzo">Elena Lorenzo</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Division of Neurosciences, Neurogenetics Laboratory, Center for Applied Medical Research, University of Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Irigoyen, Jaione" sort="Irigoyen, Jaione" uniqKey="Irigoyen J" first="Jaione" last="Irigoyen">Jaione Irigoyen</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Clinica Universidad de Navarra, University of Navarra School of Medicine</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</s1><s3>ESP</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</wicri:noRegion></affiliation></author><author><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Division of Neurosciences, Neurogenetics Laboratory, Center for Applied Medical Research, University of Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Clinica Universidad de Navarra, University of Navarra School of Medicine</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</s1><s3>ESP</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">11-0228387</idno><date when="2011">2011</date><idno type="stanalyst">PASCAL 11-0228387 INIST</idno><idno type="RBID">Pascal:11-0228387</idno><idno type="wicri:Area/PascalFrancis/Corpus">000637</idno><idno type="wicri:Area/PascalFrancis/Curation">002681</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000549</idno><idno type="wicri:doubleKey">0885-3185:2011:Lorenzo Betancor O:ling:gene:analysis</idno><idno type="wicri:Area/Main/Merge">001B39</idno><idno type="wicri:Area/Main/Curation">001880</idno><idno type="wicri:Area/Main/Exploration">001880</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">LING01 Gene Analysis in Parkinson's Disease Phenotypes</title><author><name sortKey="Lorenzo Betancor, Oswaldo" sort="Lorenzo Betancor, Oswaldo" uniqKey="Lorenzo Betancor O" first="Oswaldo" last="Lorenzo-Betancor">Oswaldo Lorenzo-Betancor</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Division of Neurosciences, Neurogenetics Laboratory, Center for Applied Medical Research, University of Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Clinica Universidad de Navarra, University of Navarra School of Medicine</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Samaranch, Lluis" sort="Samaranch, Lluis" uniqKey="Samaranch L" first="Lluís" last="Samaranch">Lluís Samaranch</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Division of Neurosciences, Neurogenetics Laboratory, Center for Applied Medical Research, University of Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Garcia Martin, Elena" sort="Garcia Martin, Elena" uniqKey="Garcia Martin E" first="Elena" last="Garcia-Martin">Elena Garcia-Martin</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Biochemistry and Molecular Biology, School of Biological Sciences, University of Extremadura</s1><s2>Badajoz</s2><s3>ESP</s3><sZ>3 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Badajoz</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>RIRMF/RETICS, Redes Temáticas de Investigación Cooperativa en Salud, Instituto de Salud Carlos III</s1><s3>ESP</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>RIRMF/RETICS, Redes Temáticas de Investigación Cooperativa en Salud, Instituto de Salud Carlos III</wicri:noRegion></affiliation></author><author><name sortKey="Cervantes, Sebastian" sort="Cervantes, Sebastian" uniqKey="Cervantes S" first="Sebastian" last="Cervantes">Sebastian Cervantes</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Division of Neurosciences, Neurogenetics Laboratory, Center for Applied Medical Research, University of Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Clinica Universidad de Navarra, University of Navarra School of Medicine</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Agundez, Jose A G" sort="Agundez, Jose A G" uniqKey="Agundez J" first="Jose A. G." last="Agundez">Jose A. G. Agundez</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>RIRMF/RETICS, Redes Temáticas de Investigación Cooperativa en Salud, Instituto de Salud Carlos III</s1><s3>ESP</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>RIRMF/RETICS, Redes Temáticas de Investigación Cooperativa en Salud, Instituto de Salud Carlos III</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Pharmacology, Medical School, University of Extremadura, Badajoz</s1><s3>ESP</s3><sZ>5 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Department of Pharmacology, Medical School, University of Extremadura, Badajoz</wicri:noRegion></affiliation></author><author><name sortKey="Jimenez Jimenez, Felix J" sort="Jimenez Jimenez, Felix J" uniqKey="Jimenez Jimenez F" first="Félix J." last="Jimenez-Jimenez">Félix J. Jimenez-Jimenez</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Department of Medicine-Neurology, Hospital Principe de Asturias, Universidad de Alcalá</s1><s2>Madrid</s2><s3>ESP</s3><sZ>6 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Neurology, Hospital del Sureste, Arganda del Rey</s1><s2>Madrid</s2><s3>ESP</s3><sZ>6 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Alonso Navarro, Hortensia" sort="Alonso Navarro, Hortensia" uniqKey="Alonso Navarro H" first="Hortensia" last="Alonso-Navarro">Hortensia Alonso-Navarro</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Neurology, Hospital La Mancha-Centro de Alcázar de San Juan</s1><s2>Ciudad Real</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Ciudad Real</wicri:noRegion></affiliation></author><author><name sortKey="Luengo, Antonio" sort="Luengo, Antonio" uniqKey="Luengo A" first="Antonio" last="Luengo">Antonio Luengo</name><affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Service of Neurology, Hospital Universitario La Princesa</s1><s2>Madrid</s2><s3>ESP</s3><sZ>8 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Coria, Francisco" sort="Coria, Francisco" uniqKey="Coria F" first="Francisco" last="Coria">Francisco Coria</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Clinic for Nervous System Disorders and Service of Neurology, Hospital Universitario Son Dureta</s1><s2>Palma de Mallorca</s2><s3>ESP</s3><sZ>9 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Palma de Mallorca</wicri:noRegion></affiliation></author><author><name sortKey="Lorenzo, Elena" sort="Lorenzo, Elena" uniqKey="Lorenzo E" first="Elena" last="Lorenzo">Elena Lorenzo</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Division of Neurosciences, Neurogenetics Laboratory, Center for Applied Medical Research, University of Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Irigoyen, Jaione" sort="Irigoyen, Jaione" uniqKey="Irigoyen J" first="Jaione" last="Irigoyen">Jaione Irigoyen</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Clinica Universidad de Navarra, University of Navarra School of Medicine</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</s1><s3>ESP</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</wicri:noRegion></affiliation></author><author><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Division of Neurosciences, Neurogenetics Laboratory, Center for Applied Medical Research, University of Navarra</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Clinica Universidad de Navarra, University of Navarra School of Medicine</s1><s2>Pamplona</s2><s3>ESP</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</s1><s3>ESP</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Nervous system diseases</term><term>Parkinson disease</term><term>Phenotype</term><term>Tremor</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Tremblement</term><term>Pathologie du système nerveux</term><term>Phénotype</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Parkinson's disease (PD) and essential tremor (ET) may share some etiopathogenic factors. A genome-wide association study has shown that LINGO1 gene variants are associated with increased risk of ET. We hypothesized that LINGO1 variants could increase susceptibility to PD. Methods: A large series of PD subjects and healthy controls were genotyped for rs9652490 and rs11856808 LINGO1 single nucleotide polymorphisms (SNPs). Results: We found an increased frequency of the rs11856808<sup>T/T</sup> genotype in PD compared with controls (odds ratio = 1.46; corrected P value = 0.02). A recessive genetic model was the best fit for rs11856808 influence on PD (recessive gene action test: corrected P value = 0.01). Stratification analysis showed that rs11856808<sup>T/T</sup> genotype frequency was higher in the tremor-dominant PD and the classical PD (C-PD) subgroups (recessive gene action test for the C-PD subgroup: corrected P value = 0.004). Discussion: Our results indicate that LINGO1 variants could increase risk of PD, specifically those presenting the non-rigid-akinetic phenotypes, which suggests that LINGO1 may have a role in the etiology of tremor in PD at least in the Spanish population.</div></front></TEI><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><country name="Espagne"><noRegion><name sortKey="Lorenzo Betancor, Oswaldo" sort="Lorenzo Betancor, Oswaldo" uniqKey="Lorenzo Betancor O" first="Oswaldo" last="Lorenzo-Betancor">Oswaldo Lorenzo-Betancor</name></noRegion><name sortKey="Agundez, Jose A G" sort="Agundez, Jose A G" uniqKey="Agundez J" first="Jose A. G." last="Agundez">Jose A. G. Agundez</name><name sortKey="Agundez, Jose A G" sort="Agundez, Jose A G" uniqKey="Agundez J" first="Jose A. G." last="Agundez">Jose A. G. Agundez</name><name sortKey="Alonso Navarro, Hortensia" sort="Alonso Navarro, Hortensia" uniqKey="Alonso Navarro H" first="Hortensia" last="Alonso-Navarro">Hortensia Alonso-Navarro</name><name sortKey="Cervantes, Sebastian" sort="Cervantes, Sebastian" uniqKey="Cervantes S" first="Sebastian" last="Cervantes">Sebastian Cervantes</name><name sortKey="Cervantes, Sebastian" sort="Cervantes, Sebastian" uniqKey="Cervantes S" first="Sebastian" last="Cervantes">Sebastian Cervantes</name><name sortKey="Coria, Francisco" sort="Coria, Francisco" uniqKey="Coria F" first="Francisco" last="Coria">Francisco Coria</name><name sortKey="Garcia Martin, Elena" sort="Garcia Martin, Elena" uniqKey="Garcia Martin E" first="Elena" last="Garcia-Martin">Elena Garcia-Martin</name><name sortKey="Garcia Martin, Elena" sort="Garcia Martin, Elena" uniqKey="Garcia Martin E" first="Elena" last="Garcia-Martin">Elena Garcia-Martin</name><name sortKey="Irigoyen, Jaione" sort="Irigoyen, Jaione" uniqKey="Irigoyen J" first="Jaione" last="Irigoyen">Jaione Irigoyen</name><name sortKey="Irigoyen, Jaione" sort="Irigoyen, Jaione" uniqKey="Irigoyen J" first="Jaione" last="Irigoyen">Jaione Irigoyen</name><name sortKey="Jimenez Jimenez, Felix J" sort="Jimenez Jimenez, Felix J" uniqKey="Jimenez Jimenez F" first="Félix J." last="Jimenez-Jimenez">Félix J. Jimenez-Jimenez</name><name sortKey="Jimenez Jimenez, Felix J" sort="Jimenez Jimenez, Felix J" uniqKey="Jimenez Jimenez F" first="Félix J." last="Jimenez-Jimenez">Félix J. Jimenez-Jimenez</name><name sortKey="Lorenzo Betancor, Oswaldo" sort="Lorenzo Betancor, Oswaldo" uniqKey="Lorenzo Betancor O" first="Oswaldo" last="Lorenzo-Betancor">Oswaldo Lorenzo-Betancor</name><name sortKey="Lorenzo, Elena" sort="Lorenzo, Elena" uniqKey="Lorenzo E" first="Elena" last="Lorenzo">Elena Lorenzo</name><name sortKey="Luengo, Antonio" sort="Luengo, Antonio" uniqKey="Luengo A" first="Antonio" last="Luengo">Antonio Luengo</name><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><name sortKey="Samaranch, Lluis" sort="Samaranch, Lluis" uniqKey="Samaranch L" first="Lluís" last="Samaranch">Lluís Samaranch</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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